Granuloma annulare is a necrobiotic disorder of unknown etiology. The clinical variants include localized, generalized, perforating and subcutaneous types. Generalized granuloma annulare is characterized by skin colored or erythematous papules in an annular configuration, with pruritus being the …
typical of interstitial granuloma annulare, which is the most common pattern reported in generalized granuloma annulare. Generalized granuloma annulare is poorly responsive to therapy.Because our patient had an unsatisfactory response to multiple treatment options, pentoxifylline was given which showed a striking response.
Some form of collagen alteration (necrobiosis) was observed in 53% of patients with generalized granuloma annulare and in 79% of patients with localized granuloma annulare.
Generalised granuloma annulare successfully treated with pentoxifylline. Rubel DM(1), Wood G, Rosen R, Jopp-McKay A. Author information: (1)Department of Dermatology, Prince of Wales Hospital, Randwick, NSW. Generalised granuloma annulare (GA) is a chronic disease of unknown aetiology and is recalcitrant to many treatment regimes.
Treatment of generalized granuloma annulare – a systematic review. Generalised granuloma annulare successfully treated with pentoxifylline. [Generalized granuloma …
Introduction: Granuloma annulare (GA) is a benign granulomatous skin disease that usually resolves within two years, but can occasionally be widespread. Generalized granuloma annulare (GGA) is a less common variant that consists of greater than ten annular plaques throughout the body.
Generalised granuloma annulare (GA) is a chronic disease of unknown aetiology and is recalcitrant to many treatment regimes. Some investigators have suggested that an immune medicated vasculitis may be involved in the pathogenesis of GA.
Generalized granuloma annulare (GGA) manifests as diffuse skin-colored to erythematous annular or nummular plaques affecting at least the trunk and either upper or lower extremities, or both. GGA is resistant to many therapeutic modalities, making it difficult to treat.
Granuloma annulare (GA) is a benign, usually self-limited dermatosis of unknown cause, characterized by necrobiotic dermal papules that often assume an annular configuration. Although localized GA is most common, the generalized variant of the disease accounts for 15% of all cases.
Granuloma annulare is a benign, usually self-limited, dermatosis of unknown cause. Generalized lesions occur in approximately 15 percent of patients with GA and may cause mild to severe cosmetic disfigurement. The treatment of generalized granuloma annulare can be challenging.
Generalized granuloma annulare: histopathology and immunopathology: systematic review of 100 cases and comparison with localized granuloma annulare. J Am Acad Dermatol. J …