Dogs with eosinophilic meningoen-cephalitis often have signs consistent with both brain and spinal cord disease; however, no report has histologically documented the spinal cord changes. In the current report, a young Rottweiler dog with an acute onset of a severe and fatal eosinophilic meningoencephalomyelitis is …
The dog was diagnosed with idiopathic eosinophilic meningoencephalomyelitis based on cerebrospinal fluid analysis, histopathology, and special stains to exclude etiologic agents.
Abstract : A 6-month-old, female, intact Rottweiler dog was presented to the Iowa State University Veterinary Teaching Hospital for a progressive history of abnormal behavior and generalized ataxia. At necropsy, there was eosinophilic infiltration of the brain and spinal cord , most severe in the medulla oblongata , cerebellum , and cervical spinal cord.
Idiopathic eosinophilic meningoencephalomyelitis in a Rottweiler dog Alicia K. Olivier,1 Jennifer D. Parkes, Heather A. Flaherty, Karen L. Kline, Joseph S. Haynes Abstract. A 6-month-old, female, intact Rottweiler dog was presented to the Iowa State University
In contrast to the previously reported cases of idiopathic canine eosinophilic meningoencephalitis, the 2 dogs reported here were female and revealed a relatively mild pleocytosis with comparatively lower numbers of eosinophils.
Eosinophilic meningoencephalomyelitis is a condition that causes the inflammation of the brain, spinal cord, and their membranes due to abnormally high numbers of eosinophils, a type of white blood cell, in the cerebrospinal fluid (CSF).
Neurological examination was consistent with a multifocal localisation. Multiple MRI scans, cerebrospinal fluid (CSF) analyses, infectious disease titres and a cerebral biopsy were performed over the course of nine months, confirming the diagnosis of idiopathic eosinophilic meningoencephalitis.
Conclusions: Idiopathic EME is a common cause of eosinophilic pleocytosis in dogs. MRI findings are variable. MRI findings are variable. Infectious causes of EME were less …
Published in: Journal of Veterinary Internal Medicine · 2009Authors: R C Windsor · Beverly K Sturges · Karen M Vernau · William VernauAffiliation: Veterinary Medical Teaching Hospital · University of California DavisAbout: Colony-stimulating factor · Eosinophil · Magnetic resonance imaging · Helminths · Eosi…
Rottweilers are also over-represented in the published reports of hypereosinophilic syndrome (HES). 2,17 HES is a rare syndrome that has been described in people, cats and less commonly in dogs. 1,2,17-19 The criteria for the definition of idiopathic HES used in people are an eosinophil count persistently greater than 1.5×10 9 /L, damage to end